Nonmotor Symptoms in Genetic Parkinson Disease
نویسندگان
چکیده
منابع مشابه
Nonmotor symptoms in patients with Parkinson disease
Parkinson disease (PD) is usually accompanied by numerous nonmotor symptoms (NMS), such as neuropsychiatric symptoms, sleep disorders, autonomic dysfunctions, and sensory disturbances. However, it is not clear that the factors influencing the occurrence of NMS and its sequence with motor symptoms (MS).We conducted comprehensive assessments of NMS by using 13 scales in 1119 PD patients.A total o...
متن کاملThe spectrum of nonmotor symptoms in early Parkinson disease.
OBJECTIVE Nonmotor symptoms (NMS) are common in patients with established Parkinson disease (PD) but their frequency in early PD has not been extensively studied. Our aim was to determine the frequency of NMS in a cohort of patients with newly diagnosed PD. METHODS A total of 159 patients with early PD and 99 healthy controls participated in this study. NMS were screened for using the nonmoto...
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BACKGROUND Although the diagnosis of Parkinson disease (PD) still relies mainly on the appearance of its classical motor features of resting tremor, rigidity, bradykinesia, and postural instability, nonmotor manifestations in PD are now recognized as an integral component of this multisystem disorder. REVIEW SUMMARY Nonmotor complications in PD occur commonly. The current understanding of cog...
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Objective: Nonmotor symptoms (sleep dysfunction, sensory symptoms, autonomic dysfunction, mood disorders, and cognitive abnormalities) in Parkinson disease (PD) are a major cause of morbidity, yet are often underrecognized. This evidence-based practice parameter evaluates treatment options for the nonmotor symptoms of PD. Articles pertaining to cognitive and mood dysfunction in PD, aswell as tr...
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Parkinson’s disease is generally thought of first and foremost as a disorder of motor control. The cardinal signs of PD are all motor defects, which generally respond favorably to dopaminergic stimulation. While the most obvious pathological change in PD is degeneration of pigmented neurons in the substantia nigra, many other neuronal pathways not involved in motor function (such as the noradre...
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ژورنال
عنوان ژورنال: Archives of Neurology
سال: 2010
ISSN: 0003-9942
DOI: 10.1001/archneurol.67.6.670